T1	Gene_expression 447 457	expression
E1	Gene_expression:T1 Theme:T2
T2	Protein 461 470	IkB-alpha
T3	Negative_regulation 475 482	inhibit
E2	Negative_regulation:T3 Cause:E1 Theme:E3
T4	Positive_regulation 487 499	upregulation
E3	Positive_regulation:T4 Theme:E4
T5	Protein 503 509	VCAM-1
T6	Gene_expression 510 520	expression
E4	Gene_expression:T6 Theme:T5
A1	Confidence E2 Possible
A2	Confidence E1 Certain
A3	Confidence E3 Certain
A4	Confidence E4 Certain
#1	AnnotatorNotes E1	The "suggest that" applies to the "inhibit", this expression event is certain.
